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dc.identifier.uri http://dx.doi.org/10.15488/17263
dc.identifier.uri https://www.repo.uni-hannover.de/handle/123456789/17391
dc.contributor.author Sun, Yunlong
dc.contributor.author Tian, Dongsong
dc.contributor.author Kuhnert, Eric
dc.contributor.author Le Goff, Geraldine
dc.contributor.author Arcile, Guillaume
dc.contributor.author Ouazzani, Jamal
dc.contributor.author Cox, Russell J.
dc.date.accessioned 2024-04-30T08:56:43Z
dc.date.available 2024-04-30T08:56:43Z
dc.date.issued 2023
dc.identifier.citation Sun, Y.; Tian, D.; Kuhnert, E.; Le Goff, G.; Arcile, G. et al.: Total biosynthesis of fungal tetraketide pyrones. In: Chemical Communications : ChemComm 59 (2023), Nr. 91, S. 13587-13590. DOI: https://doi.org/10.1039/d3cc04758j
dc.description.abstract Fungal tetraketide pyrones possess important and potent bioactivities, but their detailed biosynthetic pathways are unknown and synthetic routes to their production are lengthy. Here we investigated the fungal pathways to the multiforisins and compounds related to islandic acid. Heterologous expression experiments yield high titres of these compounds and pathway intermediates. The results both elucidate the pathway and offer a platform for the total biosynthesis of this class of metabolites. eng
dc.language.iso eng
dc.publisher Cambridge : Soc.
dc.relation.ispartofseries Chemical Communications : ChemComm 59 (2023), Nr. 91
dc.rights CC BY 3.0 Unported
dc.rights.uri https://creativecommons.org/licenses/by/3.0
dc.subject Biosynthetic Pathways eng
dc.subject Pyrones eng
dc.subject Biochemistry eng
dc.subject Fungi eng
dc.subject Metabolites eng
dc.subject.ddc 540 | Chemie
dc.title Total biosynthesis of fungal tetraketide pyrones eng
dc.type Article
dc.type Text
dc.relation.essn 1364-548X
dc.relation.issn 1359-7345
dc.relation.doi https://doi.org/10.1039/d3cc04758j
dc.bibliographicCitation.issue 91
dc.bibliographicCitation.volume 59
dc.bibliographicCitation.firstPage 13587
dc.bibliographicCitation.lastPage 13590
dc.description.version publishedVersion
tib.accessRights frei zug�nglich


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