dc.identifier.uri |
http://dx.doi.org/10.15488/14377 |
|
dc.identifier.uri |
https://www.repo.uni-hannover.de/handle/123456789/14494 |
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dc.contributor.author |
Grosse, Miriam
|
|
dc.contributor.author |
Heuser, Verena
|
|
dc.contributor.author |
Ersoy, Franziska
|
|
dc.contributor.author |
Berger, Ralf G.
|
|
dc.contributor.author |
Krings, Ulrich
|
|
dc.date.accessioned |
2023-07-31T07:00:10Z |
|
dc.date.available |
2023-07-31T07:00:10Z |
|
dc.date.issued |
2022 |
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dc.identifier.citation |
Grosse, M.; Heuser, V.; Ersoy, F.; Berger, R.G.; Krings, U.: Biogenesis of spiroketals by submerged cultured basidiomycete Trametes hirsuta. In: Mycological Progress 21 (2022), Nr. 6, 58. DOI: https://doi.org/10.1007/s11557-022-01798-w |
|
dc.description.abstract |
Volatile spiroketals are well-documented semiochemicals secreted by beetles and wasps for the intra- and interspecies communication. Its use in insect traps and as natural herbicide makes them of commercial interest. Besides insects, fungi are well-known producers, but the fungal biogenesis of spiroketals has remained speculative. Product formation along fatty acid degradation based on non-labeled feeding experiments was assumed. Thus, the observed occurrence of conophthorin and (E)- and (Z)-chalcograns in submerged cultures of the basidiomycete Trametes hirsuta prompted a precursor study aiming at a more detailed insight into their formation. Supplementation of (9Z,12 Z)-octadecadienoic (linoleic) acid resulted in elevated product yields and the identification of a fourth spiroketal, 2,8-dimethyl-1,7-dioxaspiro[5.5]-undecane. However, no intermediates of fatty acid degradation suitable as spiroketal precursors were identified. In addition, the hyphae lacked lipoxygenase activity, which was formerly supposed to be mandatory for spiroketal formation. Supplementation of 1-/2-13C acetate showed incorporation of the label into chalcogran. Therefore, a formation along the polyketide pathway analogous to insects was concluded. Graphical abstract: [Figure not available: see fulltext.] |
eng |
dc.language.iso |
eng |
|
dc.publisher |
Heidelberg : Springer |
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dc.relation.ispartofseries |
Mycological Progress 21 (2022), Nr. 6 |
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dc.rights |
CC BY 4.0 Unported |
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dc.rights.uri |
https://creativecommons.org/licenses/by/4.0 |
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dc.subject |
Chalcogran |
eng |
dc.subject |
Conophthorin |
eng |
dc.subject |
Polyketide |
eng |
dc.subject |
Spiroketals |
eng |
dc.subject |
Trametes hirsuta |
eng |
dc.subject.ddc |
580 | Pflanzen (Botanik)
|
|
dc.subject.ddc |
570 | Biowissenschaften, Biologie
|
|
dc.title |
Biogenesis of spiroketals by submerged cultured basidiomycete Trametes hirsuta |
eng |
dc.type |
Article |
|
dc.type |
Text |
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dc.relation.essn |
1861-8952 |
|
dc.relation.issn |
1617-416X |
|
dc.relation.doi |
https://doi.org/10.1007/s11557-022-01798-w |
|
dc.bibliographicCitation.issue |
6 |
|
dc.bibliographicCitation.volume |
21 |
|
dc.bibliographicCitation.firstPage |
58 |
|
dc.description.version |
publishedVersion |
eng |
tib.accessRights |
frei zug�nglich |
|
dc.bibliographicCitation.articleNumber |
58 |
|