dc.identifier.uri |
http://dx.doi.org/10.15488/14256 |
|
dc.identifier.uri |
https://www.repo.uni-hannover.de/handle/123456789/14370 |
|
dc.contributor.author |
Lücke, Daniel
|
|
dc.contributor.author |
Kalesse, Markus
|
|
dc.date.accessioned |
2023-07-24T07:18:38Z |
|
dc.date.available |
2023-07-24T07:18:38Z |
|
dc.date.issued |
2021 |
|
dc.identifier.citation |
Lücke, D.; Kalesse, M.: Synthesis of Desepoxy-Tedanolide C. In: Chemistry – A European Journal 27 (2021), Nr. 24, S. 7085-7089. DOI: https://doi.org/10.1002/chem.202100553 |
|
dc.description.abstract |
The synthesis of desepoxy-tedanolide C was accomplished and provided experimental evidence on the configuration of tedanolide C. The reported chemical shifts and coupling constants point to a configuration different from the published structure and analogous to the structures of the other members of this family of natural products. The key step is a Kiyooka aldol protocol for the stereoselective synthesis of the tertiary alcohol flanked by three additional oxygenated carbon atoms. Furthermore, two additional aldol reactions and a Julia–Kocienski olefination were used to assemble the carbon framework. |
eng |
dc.language.iso |
eng |
|
dc.publisher |
Weinheim : Wiley-VCH |
|
dc.relation.ispartofseries |
Chemistry – A European Journal 27 (2021), Nr. 24 |
|
dc.rights |
CC BY-NC-ND 4.0 Unported |
|
dc.rights.uri |
https://creativecommons.org/licenses/by-nc-nd/4.0 |
|
dc.subject |
Kiyooka aldol |
eng |
dc.subject |
polyketides |
eng |
dc.subject |
structure elucidation |
eng |
dc.subject |
tedanolie C |
eng |
dc.subject |
tertiary alcohol |
eng |
dc.subject.ddc |
540 | Chemie
|
|
dc.subject.ddc |
660 | Technische Chemie
|
|
dc.title |
Synthesis of Desepoxy-Tedanolide C |
eng |
dc.type |
Article |
|
dc.type |
Text |
|
dc.relation.essn |
1521-3765 |
|
dc.relation.issn |
0947-6539 |
|
dc.relation.doi |
https://doi.org/10.1002/chem.202100553 |
|
dc.bibliographicCitation.issue |
24 |
|
dc.bibliographicCitation.volume |
27 |
|
dc.bibliographicCitation.firstPage |
7085 |
|
dc.bibliographicCitation.lastPage |
7089 |
|
dc.description.version |
publishedVersion |
eng |
tib.accessRights |
frei zug�nglich |
|