Formulation of Functional Drink with Milk Fortification: Effects on the Bioaccessibility and Intestinal Absorption of Phenolics

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Ozkan, G.; Capanoglu, E.; Esatbeyoglu, T.: Formulation of Functional Drink with Milk Fortification: Effects on the Bioaccessibility and Intestinal Absorption of Phenolics. In: Plants 11 (2022), Nr. 23, 3364. DOI: https://doi.org/10.3390/plants11233364

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To cite the version in the repository, please use this identifier: https://doi.org/10.15488/13927

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Sum total of downloads: 22




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Abstract: 
Due to a turn toward to functional foods with improved nutritional value, rosehip could be an appropriate candidate to create formulations using a milk matrix. In the present study, the influence of bovine or almond milk fortification on the bioaccessibility and intestinal absorption of rosehip infusion phenolics, mainly catechin, were investigated by a combined method of an in vitro gastrointestinal digestion/Caco-2 cell culture model. The results indicated that bovine (IB) or almond milk (IA) fortification enhanced the retention of total phenolics (TPC; increase of 8.1% and 20.3% for IB and IA, respectively), while there was a decline in the total flavonoids (TFC; decrease of 64% and 17% for IB and IA, respectively) and antioxidant capacity measured by CUPRAC assay (decrease of 15% and 4% for IB and IA, respectively) throughout the gastrointestinal tract in comparison with the control sample (IC). Then, based on the cytotoxicity (SRB) assay, 1/5 times diluted digests were subjected to transepithelial transportation of Caco-2 cells. According to the results, the bovine milk matrix positively affected the transportation of phenolics across the epithelial cell layer. It could be concluded that it is possible to produce functional infusion drinks with improved stability, bioaccessibility, and absorption efficiency of rosehip phenolics in the formulations containing milk matrix.
License of this version: CC BY 4.0 Unported
Document Type: Article
Publishing status: publishedVersion
Issue Date: 2022
Appears in Collections:Fakultät für Mathematik und Physik

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pos. country downloads
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1 image of flag of United States United States 9 40.91%
2 image of flag of Germany Germany 8 36.36%
3 image of flag of Europe Europe 2 9.09%
4 image of flag of Vietnam Vietnam 1 4.55%
5 image of flag of Indonesia Indonesia 1 4.55%
6 image of flag of United Kingdom United Kingdom 1 4.55%

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