We present new evidence for seven deep crustal, intraplate earthquakes in northern Germany, a region regarded as an area of low seismicity. From 2000 to 2018, seven earthquakes with magnitudes of ML 1.3–3.1, were detected at depths of 17.0–31.4 km. By placing the earthquake hypocentres in a geological three-dimensional model, we can correlate two of the earthquakes with the Thor Suture, a major fault zone in this area. Five of the earthquakes group in the lower crust near the Moho, which implies that parts of the lower crust and the crust/mantle boundary in northern Germany act as a structural discontinuity on which deformation localizes. Numerical simulation implies that stress changes due to glacial isostatic adjustment most likely triggered these deep crustal earthquakes.