A fault gouge forms at the core of the fault as the result of a slip in the upper brittle crust. Therefore, the deformation mechanisms and conditions under which the fault gouge was formed can document the stages of fault movement in the crust. We carried out a microstructural analysis on a fault gouge from a hanging-wall branch fault of the Simplon Fault Zone, a major low-angle normal fault in the Alps. We use thin-section analysis, together with backscattered electron imaging and X-ray diffractometry (XRD), to show that a multistage history from ductile to brittle deformation, together with a continuous exhumation history from high to low temperature, took place within the fault gouge. Because of the predominance of pressure solution and veining, we associated a large part of the deformation in the fault gouge with viscous-frictional behaviour that occurred at the brittle-ductile transition. Phyllosilicates and graphite likely caused fault lubrication that we suggested played a role in the formation of this major low-angle normal fault. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.