- Home
- →
- Fakultäten
- →
- Naturwissenschaftliche Fakultät
- →
- View Item
Download statistics - Document (COUNTER):
Feng, J.; Surup, F.; Hauser, M.; Miller, A.; Wennrich, J.-P. et al.: Biosynthesis of oxygenated brasilane terpene glycosides involves a promiscuous N-acetylglucosamine transferase. In: Chemical Communications 56 (2020), Nr. 82, S. 12419-12422. DOI: https://doi.org/10.1039/d0cc03950k
Repository version
Selected time period:
Sum total of downloads: 35
| Abstract: | |
Investigation of the metabolome of the ascomycete Annulohypoxylon truncatum led to the identification of novel oxygenated brasilane glycosides and the revision of the stereochemistry of the brasilane A octahydro-1H-indene core scaffold to trans. The bra biosynthetic gene cluster containing five genes (braA–braE) was identified and verified by heterologous expression experiments in Aspergillus oryzae demonstrating that BraC is a multifunctional P450 monooxygenase. In vitro studies of BraB revealed it to be a very rare fungal UDP-GlcNAc dependent N-acetylglucosamine transferase. UDP-glucose is also accepted as a donor, and a broad acceptor substrate tolerance for various primary and secondary alcohols was observed. | |
| License of this version: | CC BY 3.0 Unported |
| Document Type: | Article |
| Publishing status: | publishedVersion |
| Issue Date: | 2020 |
| Appears in Collections: | Naturwissenschaftliche Fakultät |
distribution of downloads over the selected time period:
downloads by country:
| pos. | country | downloads | ||
|---|---|---|---|---|
| total | perc. | |||
| 1 |  |
Germany | 16 | 45.71% |
| 2 |  |
United States | 8 | 22.86% |
| 3 |  |
China | 4 | 11.43% |
| 4 |  |
Indonesia | 2 | 5.71% |
| 5 |  |
Taiwan | 1 | 2.86% |
| 6 |  |
Korea, Republic of | 1 | 2.86% |
| 7 |  |
Iran, Islamic Republic of | 1 | 2.86% |
| 8 |  |
Switzerland | 1 | 2.86% |
| 9 |  |
Brazil | 1 | 2.86% |
Further download figures and rankings:
Hinweis
Zur Erhebung der Downloadstatistiken kommen entsprechend dem „COUNTER Code of Practice for e-Resources“ international anerkannte Regeln und Normen zur Anwendung. COUNTER ist eine internationale Non-Profit-Organisation, in der Bibliotheksverbände, Datenbankanbieter und Verlage gemeinsam an Standards zur Erhebung, Speicherung und Verarbeitung von Nutzungsdaten elektronischer Ressourcen arbeiten, welche so Objektivität und Vergleichbarkeit gewährleisten sollen. Es werden hierbei ausschließlich Zugriffe auf die entsprechenden Volltexte ausgewertet, keine Aufrufe der Website an sich.