Browsing by Subject "hypoxia sensor"

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Hypoxia Onset in Mesenchymal Stem Cell Spheroids: Monitoring With Hypoxia Reporter Cells

Schmitz, Carola; Potekhina, Ekaterina; Belousov, Vsevolod V.; Lavrentieva, Antonina (Lausanne : Frontiers Media, 2021)

The therapeutic and differentiation potential of human mesenchymal stems cells (hMSCs) makes these cells a promising candidate for cellular therapies and tissue engineering. On the path of a successful medical application ...
Live reporting for hypoxia : Hypoxia sensor–modified mesenchymal stem cells as in vitro reporters

Schmitz, Carola; Pepelanova, Iliyana; Seliktar, Dror; Potekhina, Ekaterina; Belousov, Vsevolod V.; Scheper, Thomas; Lavrentieva, Antonina (New York, NY [u.a.] : Wiley, 2020)

Natural oxygen gradients occur in tissues of biological organisms and also in the context of three-dimensional (3D) in vitro cultivation. Oxygen diffusion limitation and metabolic oxygen consumption by embedded cells produce ...
Studies on oxygen availability and the creation of natural and artificial oxygen gradients in gelatin-methacryloyl hydrogel 3D cell culture

Schmitz, Carola; Pepelanova, Iliyana; Ude, Christian; Lavrentieva, Antonina (Hoboken, NJ [u.a.] : Wiley, 2022)

Three-dimensional (3D) cultivation platforms allow the creation of cell models, which more closely resemble in vivo-like cell behavior. Therefore, 3D cell culture platforms have started to replace conventional two-dimensional ...

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