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Browsing by Subject "human pluripotent stem cells"

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EBIO Does Not Induce Cardiomyogenesis in Human Pluripotent Stem Cells but Modulates Cardiac Subtype Enrichment by Lineage-Selective Survival

Jara-Avaca, Monica; Kempf, Henning; Rückert, Michael; Robles-Diaz, Diana; Franke, Annika; de la Roche, Jeanne; Fischer, Martin; Malan, Daniela; Sasse, Philipp; Solodenko, Wladimir; Dräger, Gerald; Kirschning, Andreas; Martin, Ulrich; Zweigerdt, Robert (New York, NY : Springer, 2017)

Subtype-specific human cardiomyocytes (CMs) are valuable for basic and applied research. Induction of cardiomyogenesis and enrichment of nodal-like CMs was described for mouse pluripotent stem cells (mPSCs) in response to ...
High Density Bioprocessing of Human Pluripotent Stem Cells by Metabolic Control and in Silico Modeling

Manstein, Felix; Ullmann, Kevin; Kropp, Christina; Halloin, Caroline; Triebert, Wiebke; Franke, Annika; Farr, Clara-Milena; Sahabian, Anais; Haase, Alexandra; Breitkreuz, Yannik; Peitz, Michael; Brüstle, Oliver; Kalies, Stefan; Martin, Ulrich; Olmer, Ruth; Zweigerdt, Robert (Oxford : Oxford University Press, 2021)

To harness the full potential of human pluripotent stem cells (hPSCs) we combined instrumented stirred tank bioreactor (STBR) technology with the power of in silico process modeling to overcome substantial, hPSC-specific ...
Sensitivity of human pluripotent stem cells to insulin precipitation induced by peristaltic pump-based medium circulation: Considerations on process development

Massai, Diana; Bolesani, Emiliano; Diaz, Diana R.; Kropp, Christina; Kempf, Henning; Halloin, Caroline; Martin, Ulrich; Braniste, Tudor; Isu, Giuseppe; Harms, Vanessa; Morbiducci, Umberto; Dräger, Gerald; Zweigerdt, Robert (London : Nature Publishing Group, 2017)

Controlled large-scale production of human pluripotent stem cells (hPSCs) is indispensable for their envisioned clinical translation. Aiming at advanced process development in suspension culture, the sensitivity of hPSC ...

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Browsing by Subject "human pluripotent stem cells"

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