Browsing by Subject "Transposon vector"

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Transgene Expression and Transposition Efficiency of Two-Component Sleeping Beauty Transposon Vector Systems Utilizing Plasmid or mRNA Encoding the Transposase

Tschorn, Natalie; van Heuvel, Yasemin; Stitz, Jörn (New York, NY : Springer, 2022)

The use of two-component transposon plasmid vector systems, namely, a transposase construct and a donor vector carrying the gene of interest (GOI) can accelerate the development of recombinant cell lines. However, the ...
Transposon vector-mediated stable gene transfer for the accelerated establishment of recombinant mammalian cell pools allowing for high-yield production of biologics

Tschorn, Natalie; Berg, Karen; Stitz, Jörn (Dordrecht [u.a.] : Springer Science + Business Media B.V, 2020)

Stable recombinant mammalian cells are of growing importance in pharmaceutical biotechnology production scenarios for biologics such as monoclonal antibodies, growth and blood factors, cytokines and subunit vaccines. ...

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