Browsing by Subject "Drug targeting"

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Biodistribution, biocompatibility and targeted accumulation of magnetic nanoporous silica nanoparticles as drug carrier in orthopedics

Janßen, Hilke Catherina; Angrisani, Nina; Kalies, Stefan; Hansmann, Florian; Kietzmann, Manfred; Warwas, Dawid Peter; Behrens, Peter; Reifenrath, Janin (London : BioMed Central Ltd., 2020)

Background: In orthopedics, the treatment of implant-associated infections represents a high challenge. Especially, potent antibacterial effects at implant surfaces can only be achieved by the use of high doses of antibiotics, ...
In vitro and in vivo accumulation of magnetic nanoporous silica nanoparticles on implant materials with different magnetic properties

Janßen, Hilke Catherina; Dahlhaus, David; Warwas, Dawid Peter; Meißner, Jessic; Taptimthong, Piriya; Kietzmann, Manfred; Behrens, Pete; Reifenrath, Janin; Angrisani, Nina (Berlin : Springer Nature, 2018)

Background: In orthopedic surgery, implant-associated infections are still a major problem. For the improvement of the selective therapy in the infection area, magnetic nanoparticles as drug carriers are promising when ...

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