Auflistung nach Schlagwort "Hsp90"

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  • Synthetic studies towards the SNAC ester of seco-progeldanamycin 
    Bartens, Christian (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2022)
    The ansamycin antibiotic geldanamycin is biosynthesized by Streptomyces hygroscopicus through a PKS type I. The macrolactamization in the biosynthesis is catalyzed by the amide synthase GdmF. GdmF belongs to the superfamily ...
  • Triiodothyronine Acts as a Smart Influencer on Hsp90 via a Triiodothyronine Binding Site 
    Fan, Lu; Warnecke, Athanasia; Weder, Julia; Preller, Matthias; Zeilinger, Carsten (Basel : Molecular Diversity Preservation International (MDPI), 2022)
    Microarray-based experiments revealed that thyroid hormone triiodothyronine (T3) enhanced the binding of Cy5-labeled ATP on heat shock protein 90 (Hsp90). By molecular docking experiments with T3 on Hsp90, we identified a ...